RSPH10B2

Across TCGA cell cohorts, RSPH10B2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RSPH10B2-associated genes across cancer lineages are VSX2, BRDT, and RASGEF1C. Each is linked with RSPH10B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RSPH10B2-to-partner and partner-to-RSPH10B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VSX2 grouped by RSPH10B2-low versus RSPH10B2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSPH10B2→partner) and Y-score (partner→RSPH10B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	VSX2 →	+0.016	+2.994	.001	.006	3	1
LARGE_INTESTINE	BRDT →	+0.119	+4.169	<.001	<.001	3	1
LARGE_INTESTINE	RASGEF1C →	+0.288	+3.333	<.001	.009	3	1
LARGE_INTESTINE	ACER1 →	+0.117	+3.145	<.001	.004	3	1
LARGE_INTESTINE	TECRL →	+0.012	+3.562	<.001	.002	3	1
LARGE_INTESTINE	OR5V1 →	+0.005	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

VSX2 by RSPH10B2 expression — LARGE_INTESTINE

Explore this box plot interactively →