RSPH10B2

Across TCGA cell cohorts, RSPH10B2 mutation is significantly associated with the mutation status of many other genes, with 2,206 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RSPH10B2-associated genes across cancer lineages are TAFA5, UTP11, and PIK3CA. Each is linked with RSPH10B2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RSPH10B2-to-partner and partner-to-RSPH10B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAFA5 grouped by RSPH10B2-low versus RSPH10B2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSPH10B2→partner) and Y-score (partner→RSPH10B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TAFA5 →	+6.321	+6.321	.001	.001	1	3
LARGE_INTESTINE	UTP11 →	+3.584	+3.007	.008	.008	1	3
BLOOD_Leukemia	PIK3CA →	+4.000	+5.050	.008	.008	1	3
LARGE_INTESTINE	ARMCX3 →	+2.678	+2.807	.006	.006	1	3
LARGE_INTESTINE	FYN →	+3.000	+3.369	<.001	<.001	1	3
LARGE_INTESTINE	MAP3K12 →	+3.000	+3.000	.003	.003	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,206 associations by consensus.

TAFA5 by RSPH10B2 expression — BLOOD_Leukemia

Explore this box plot interactively →