RSPH10B

Across TCGA patient cohorts, RSPH10B mutation is significantly associated with the RNA expression of many other genes, with 328 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSPH10B-associated genes across cancer lineages are RNU6-44P, LINC00208, and OR52Z1. Each is linked with RSPH10B in more than 1 cancer types. Because this analysis shows association rather than direction, both RSPH10B-to-partner and partner-to-RSPH10B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-44P grouped by RSPH10B-low versus RSPH10B-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSPH10B→partner) and Y-score (partner→RSPH10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-44P →	+0.321	+5.407	<.001	<.001	3	2
HNSC	LINC00208 →	+0.023	+4.498	<.001	.002	3	1
HNSC	OR52Z1 →	+0.038	+5.178	<.001	.002	3	1
HNSC	OR52B1P →	+0.047	+3.988	.009	.005	3	1
HNSC	RNA5SP218 →	+0.631	+3.748	<.001	.008	3	1
HNSC	RNU6-1020P →	+0.299	+4.548	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 328 associations by consensus.

RNU6-44P by RSPH10B expression — HNSC

Explore this box plot interactively →