RSPH10B

Across TCGA patient cohorts, RSPH10B mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSPH10B-associated genes across cancer lineages are ASNS, eIF4G, and ER-alpha. Each is linked with RSPH10B in more than 1 cancer types. Because this analysis shows association rather than direction, both RSPH10B-to-partner and partner-to-RSPH10B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by RSPH10B-low versus RSPH10B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSPH10B→partner) and Y-score (partner→RSPH10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.413	+3.321	.029	.010	3	2
UCEC	eIF4G →	+0.381	+2.999	.019	.035	3	1
UCEC	ER-alpha →	-0.885	-2.986	.039	.035	3	1
UCEC	AMPK_alpha →	-0.250	-3.000	.012	.036	3	1
UCEC	Shc_pY317 →	-0.215	-3.000	.006	.036	3	1
UCEC	VEGFR2 →	+0.446	+3.179	.004	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

ASNS by RSPH10B expression — UCEC

Explore this box plot interactively →