RSPH10B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RSPH10B mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RSPH10B-associated genes across cancer lineages are RFPL3 and OR6Q1. Each is linked with RSPH10B in more than 1 cancer types. Because this analysis shows association rather than direction, both RSPH10B-to-partner and partner-to-RSPH10B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RFPL3 grouped by RSPH10B-low versus RSPH10B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSPH10B→partner) and Y-score (partner→RSPH10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINERFPL3 →+0.040+4.095.001.00931
LARGE_INTESTINEOR6Q1 →+0.022+5.022<.001.00231
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

RFPL3 by RSPH10B expression — LARGE_INTESTINE

Box plot of RFPL3 in RSPH10B-low vs RSPH10B-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration