RSL24D1

Across TCGA pan-cancer cohorts, RSL24D1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RSL24D1 data layer compared with 21 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher RSL24D1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RSL24D1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

LSCC, PDAC, and LUAD are the cancer types where RSL24D1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	II,III,IV	0.939	0.474	.003	23	view →
PDAC	OS	Tertile	II,III,IV	0.337	0.738	.004	19	view →
LUAD	OS	Median	All	0.792	1.000	.014	7	view →
CCRCC	DFS	Quartile	All	0.601	0.935	.011	6	view →
HNSC	DFS	Median	IV	0.551	0.769	.019	2	view →
GBM	DFS	Median	All	0.799	0.533	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RSL24D1–LSCC (DFS)

Open the LSCC breakdown →