RSL24D1

Across TCGA pan-cancer cohorts, RSL24D1 mass-spec protein differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RSL24D1’s most consistent transcriptional readouts.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where RSL24D1 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types RSL24D1 is over-expressed in tumor, although a few such as PDAC and HNSC show the opposite, repressed pattern.

CCRCC, COAD, and LSCC are the cancer types where RSL24D1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RSL24D1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
CCRCC	All	III,IV	+0.444	<.001	11	view →
COAD	Female	II,III,IV	+0.425	<.001	8	view →
LSCC	Male	II,III,IV	+0.466	<.001	7	view →
PDAC	Female	All	−0.989	<.001	6	view →
HNSC	Male	All	−0.177	.031	4	view →
LUAD	All	All	+0.153	.003	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RSL24D1–CCRCC

Open the CCRCC breakdown →