RSF1

Across TCGA patient cohorts, RSF1 mutation is significantly associated with the RNA expression of many other genes, with 3,903 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSF1-associated genes across cancer lineages are IL9, SFXN1, and GAGE2E. Each is linked with RSF1 in more than 3 cancer types. Because this analysis shows association rather than direction, both RSF1-to-partner and partner-to-RSF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL9 grouped by RSF1-low versus RSF1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSF1→partner) and Y-score (partner→RSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	IL9 →	+0.077	+3.929	.008	<.001	3	4
COAD	SFXN1 →	+0.512	+3.479	.001	.002	3	4
HNSC	GAGE2E →	+0.176	+4.023	<.001	.009	3	4
UCEC	MRPL54 →	+0.402	+3.332	<.001	<.001	3	4
UCEC	NDUFC1 →	+0.285	+2.212	.002	.001	3	3
UCEC	RPL26L1 →	+0.387	+2.480	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,903 associations by consensus.

IL9 by RSF1 expression — BLCA

Explore this box plot interactively →