RSF1

Across TCGA cell cohorts, RSF1 mutation is significantly associated with the RNA expression of many other genes, with 46 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RSF1-associated genes across cancer lineages are AVP, MINDY4B, and KRTAP10-5. Each is linked with RSF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RSF1-to-partner and partner-to-RSF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by RSF1-low versus RSF1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSF1→partner) and Y-score (partner→RSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	2
LUNG_NSCLC_LUAD	MINDY4B →	+0.011	+5.472	<.001	<.001	3	2
LUNG_NSCLC_LUAD	KRTAP10-5 →	+0.014	+4.662	<.001	.005	3	2
BLOOD_Myeloma	USP17L4 →	+0.040	+4.807	<.001	.006	3	1
PANCREAS	LINC02881 →	+0.019	+5.000	<.001	.006	3	1
BREAST	OOSP2 →	+0.011	+3.781	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

AVP by RSF1 expression — BLOOD_Lymphoma

Explore this box plot interactively →