RSBN1L

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RSBN1L Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RSBN1L data layer compared with 24 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RSBN1L Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RSBN1L expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

KIRP, UCEC, and COAD are the cancer types where RSBN1L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRPOSMedianAll0.2720.885<.00112view →
UCECDFSMedianAll1.0000.622.00312view →
COADOSMedianAll0.1320.674.0018view →
MESODFSMedianAll0.0980.366.0396view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration