Across TCGA patient cohorts, RSBN1L mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSBN1L-associated genes across cancer lineages are FOXO3a_pS318_S321, Caspase-7-cleavedD198, and EGFR_pY1068. Each is linked with RSBN1L in more than 1 cancer types. Because this analysis shows association rather than direction, both RSBN1L-to-partner and partner-to-RSBN1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSBN1L→partner) and Y-score (partner→RSBN1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a_pS318_S321 →	-0.097	-1.575	.031	.034	3	2
UCEC	Caspase-7-cleavedD198 →	+0.563	+1.720	.008	.025	3	2
UCEC	EGFR_pY1068 →	-0.221	-1.925	.014	.005	3	1
UCEC	eIF4E →	+0.194	+2.321	.010	.001	3	1
UCEC	FASN →	+0.366	+2.222	.009	.010	3	1
UCEC	Fibronectin →	-0.272	-2.212	.022	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

RSBN1L survival (RNA) · tumor vs normal (RNA) · all RSBN1L data types