Across TCGA cell cohorts, RSBN1L mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible RSBN1L-associated genes across cancer lineages are NLRP2B, DEFB118, and FAM135B. Each is linked with RSBN1L in more than 1 cancer types. Because this analysis shows association rather than direction, both RSBN1L-to-partner and partner-to-RSBN1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSBN1L→partner) and Y-score (partner→RSBN1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	NLRP2B →	+0.009	+3.882	<.001	.001	3	2
BLOOD_Myeloma	DEFB118 →	+0.020	+4.807	<.001	.006	3	1
URINARY_TRACT	FAM135B →	+0.021	+4.217	<.001	.005	3	1
URINARY_TRACT	CCDC178 →	+0.030	+4.087	<.001	.009	3	1
URINARY_TRACT	PRAMEF25 →	+0.010	+4.087	<.001	.009	3	1
SKIN	HBZ →	+0.069	+3.453	.007	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

RSBN1L survival (RNA) · tumor vs normal (RNA) · all RSBN1L data types