RSBN1

Across TCGA pan-cancer cohorts, RSBN1 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated RSBN1 data layer compared with 28 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher RSBN1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated RSBN1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

LSCC, HNSC, and PDAC are the cancer types where RSBN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	II,III,IV	0.913	0.633	.002	24	view →
HNSC	OS	Median	II,III,IV	0.795	0.913	.027	15	view →
PDAC	OS	Tertile	II,III,IV	0.249	0.552	.007	13	view →
CCRCC	OS	Tertile	All	1.000	0.677	.017	11	view →
UCEC	DFS	Tertile	All	0.807	0.963	.014	8	view →
COAD	DFS	Median	All	1.000	0.869	.041	6	view →
GBM	OS	Median	All	0.656	0.415	.008	6	view →
LUAD	DFS	Quartile	III,IV	0.453	0.861	.022	4	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RSBN1–LSCC (OS)

Open the LSCC breakdown →