RRP9

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RRP9 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated RRP9 data layer compared with 26 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RRP9 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated RRP9 expression acts as an unfavorable survival marker.

ACC and SKCM are the cancer types where RRP9 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCDFSMedianAll0.1950.748.0033view →
SKCMDFSMedianIII,IV0.0150.648<.0013view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

RRP9–ACC (DFS)

Kaplan–Meier survival curve for RRP9 mutant vs wild-type samples in ACC.

Open the ACC breakdown →

Exploration