RRP8

Across TCGA pan-cancer cohorts, RRP8 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated RRP8 data layer compared with 17 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RRP8 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RRP8 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

CCRCC, PDAC, and LSCC are the cancer types where RRP8 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	IV	0.451	1.000	.016	25	view →
PDAC	OS	Quartile	All	0.646	0.410	.008	6	view →
LSCC	OS	Median	III,IV	0.664	0.996	.015	5	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

RRP8–CCRCC (OS)

Open the CCRCC breakdown →