Q-omics provides the consensus-scored RRP7BP profile across patient tissues and cancer cell-line models. RRP7BP expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, RRP7BP is differentially expressed in 12, with the highest sampling consensus in COAD. Additionally, RRP7BP RNA expression shows 19,762 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight ACC, COAD, and UVM as cancer lineages where RRP7BP shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RRP7BP — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RRP7BP survival associations across molecular data types. RRP7BP RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RRP7BP RNA expression–survival associations across cancer types. High RRP7BP expression shows unfavorable associations in ACC, KIRC, COAD and LIHC, but favorable associations in READ and BLCA. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for RRP7BP RNA expression.
This table summarizes RRP7BP tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for RRP7BP. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RRP7BP shows higher tumor expression in COAD, LIHC, HNSC, STAD, LUAD and BLCA. The COAD box plot shows higher RRP7BP RNA expression in tumor versus normal tissue (log2 FC = +1.122, t-test p < 0.001).
This table shows molecular features associated with RRP7BP in patient tissues and cancer cell lines. In patient samples, RRP7BP shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
