Across TCGA patient cohorts, RRP7A protein abundance is significantly associated with the RNA expression of many other genes, with 15,865 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RRP7A-associated genes across cancer lineages are WDR43, FOXM1, and CENPA. Each is linked with RRP7A in more than 7 cancer types. Because this analysis shows association rather than direction, both RRP7A-to-partner and partner-to-RRP7A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRP7A→partner) and Y-score (partner→RRP7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WDR43 →	+0.777	+0.432	<.001	<.001	3	8
BRCA	FOXM1 →	+0.979	+0.229	<.001	<.001	3	7
BRCA	CENPA →	+1.308	+0.335	<.001	<.001	3	7
GBM	NCAPH →	+0.865	+0.268	<.001	<.001	3	7
LSCC	RRM2 →	+0.889	+0.256	<.001	<.001	3	7
BRCA	KIF18B →	+1.083	+0.389	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,865 associations by consensus.

Exploration

RRP7A survival (RNA) · tumor vs normal (RNA) · all RRP7A data types