RRP15

Across TCGA pan-cancer cohorts, RRP15 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated RRP15 data layer compared with 25 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RRP15 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RRP15 expression acts as an unfavorable survival marker, although some lineages such as LUAD and COAD show a favorable association.

LUAD, CCRCC, and COAD are the cancer types where RRP15 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.996	0.808	<.001	67	view →
CCRCC	DFS	Tertile	All	0.694	0.939	.001	41	view →
COAD	DFS	Median	All	1.000	0.919	.013	36	view →
PDAC	OS	Tertile	II,III,IV	0.553	0.383	.024	18	view →
OV	DFS	Tertile	All	0.610	0.923	.031	4	view →
HNSC	OS	Median	III,IV	0.344	1.000	.009	4	view →
LSCC	DFS	Median	II,III,IV	0.808	0.597	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RRP15–LUAD (DFS)

Open the LUAD breakdown →