RRP15

Across TCGA patient cohorts, RRP15 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RRP15-associated genes across cancer lineages are MPP, Macrophages M2, and Mesangial cells. Each is linked with RRP15 in more than 1 cancer types. Because this analysis shows association rather than direction, both RRP15-to-partner and partner-to-RRP15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by RRP15-low versus RRP15-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRP15→partner) and Y-score (partner→RRP15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MPP →	+0.018	+2.818	.043	.023	3	1
UCEC	Macrophages M2 →	+0.010	+2.831	.042	.035	3	1
UCEC	Mesangial cells →	-0.052	-2.574	.003	.011	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MPP by RRP15 expression — COAD

Explore this box plot interactively →