RRP15

Across TCGA cell cohorts, RRP15 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RRP15-associated genes across cancer lineages are HTR5A, MC2R, and RBMY1J. Each is linked with RRP15 in more than 1 cancer types. Because this analysis shows association rather than direction, both RRP15-to-partner and partner-to-RRP15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HTR5A grouped by RRP15-low versus RRP15-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRP15→partner) and Y-score (partner→RRP15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	HTR5A →	+0.143	+4.930	<.001	.008	3	1
SOFT_TISSUE	MC2R →	+0.073	+5.977	<.001	.001	3	1
SOFT_TISSUE	RBMY1J →	+0.031	+4.930	<.001	.008	3	1
LUNG_NSCLC_LUAD	SERPINA7 →	+0.006	+5.228	.005	.005	3	1
LUNG_NSCLC_LUAD	OR4K1 →	+0.019	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	LCE2C →	+0.042	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

HTR5A by RRP15 expression — SOFT_TISSUE

Explore this box plot interactively →