RRP1

Across TCGA pan-cancer cohorts, RRP1 RNA differs between tumor and matched normal tissue in 17 of 18 cancer types tested, making tumor–normal expression one of RRP1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RRP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RRP1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

COAD, KIRC, and STAD are the cancer types where RRP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RRP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	+1.486	<.001	12	view →
KIRC	Female	All	+0.820	<.001	12	view →
STAD	Male	II,III,IV	+1.219	<.001	10	view →
LIHC	Female	II,III,IV	+1.271	<.001	9	view →
LUAD	Female	III,IV	+0.972	<.001	9	view →
BLCA	Male	III,IV	+1.405	<.001	8	view →
HNSC	Male	All	+0.678	<.001	8	view →
LUSC	Male	III,IV	+1.429	<.001	7	view →
KIRP	All	III,IV	+0.631	<.001	7	view →
UCEC	All	All	+0.512	.002	6	view →
CHOL	Male	All	+1.736	<.001	5	view →
BRCA	All	All	+0.390	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 17 lineages.

RRP1–COAD

Open the COAD breakdown →