RRN3P3

Across TCGA pan-cancer cohorts, RRN3P3 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RRN3P3 data layer compared with 1 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RRN3P3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RRN3P3 expression acts as an unfavorable survival marker, although some lineages such as BLCA and THYM show a favorable association.

ACC, BLCA, and UVM are the cancer types where RRN3P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Quartile	All	0.373	0.871	<.001	71	view →
BLCA	OS	Median	II,III,IV	0.787	0.645	.001	61	view →
UVM	DFS	Quartile	III,IV	0.239	0.809	.002	46	view →
LIHC	DFS	Tertile	All	0.415	0.594	<.001	40	view →
SKCM	DFS	Tertile	III,IV	0.114	0.498	.001	35	view →
LGG	DFS	Tertile	All	0.658	0.824	<.001	31	view →
KIRC	DFS	Tertile	II,III,IV	0.369	0.625	.003	30	view →
THYM	OS	Median	All	1.000	0.743	.001	23	view →
CHOL	DFS	Median	III,IV	0.127	0.647	.006	12	view →
HNSC	OS	Quartile	All	0.765	0.624	.014	12	view →
PRAD	DFS	Quartile	All	0.647	0.893	.004	10	view →
MESO	DFS	Median	All	0.464	0.319	.033	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RRN3P3–ACC (OS)

Open the ACC breakdown →