RRN3P3

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RRN3P3 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated RRN3P3 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RRN3P3 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated RRN3P3 expression acts as an unfavorable survival marker.

LUSC are the cancer types where RRN3P3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUSCDFSMedianII,III,IV0.1390.663.0276view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

RRN3P3–LUSC (DFS)

Kaplan–Meier survival curve for RRN3P3 mutant vs wild-type samples in LUSC.

Open the LUSC breakdown →

Exploration