RRN3

Across TCGA patient cohorts, RRN3 protein abundance is significantly associated with the RNA expression of many other genes, with 17,701 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RRN3-associated genes across cancer lineages are DIPK2B, MAMDC2, and MOB3C. Each is linked with RRN3 in more than 3 cancer types. Because this analysis shows association rather than direction, both RRN3-to-partner and partner-to-RRN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RRN3 versus DIPK2B in BRCA, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRN3→partner) and Y-score (partner→RRN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DIPK2B →	-0.771	-0.325	<.001	<.001	3	3
OV	MAMDC2 →	-1.049	-0.484	.001	.006	2	4
BRCA	MOB3C →	-0.306	-0.202	.001	<.001	3	3
LUAD	ABCA10 →	-0.586	-0.216	<.001	.005	3	3
BRCA	GPD1 →	-1.373	-0.262	.004	.001	3	3
BRCA	VENTX →	-0.474	-0.251	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,701 associations by consensus.

RRN3 vs DIPK2B — BRCA

Explore this scatter interactively →