RRN3

Across TCGA cell cohorts, RRN3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,066 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible RRN3-associated genes across cancer lineages are TIMELESS, MERTK, and QPCTL. Each is linked with RRN3 in more than 3 cancer types. Because this analysis shows association rather than direction, both RRN3-to-partner and partner-to-RRN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RRN3 versus TIMELESS in LARGE_INTESTINE, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRN3→partner) and Y-score (partner→RRN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TIMELESS →	+0.681	+0.930	<.001	<.001	3	4
BLOOD_Lymphoma	MERTK →	+0.732	+0.532	.002	.005	3	4
STOMACH	QPCTL →	-0.859	-1.809	.002	.006	3	3
LARGE_INTESTINE	JPH1 →	+0.617	+0.575	.009	.006	2	4
LARGE_INTESTINE	TERF2 →	+0.606	+0.690	.008	.004	3	3
LARGE_INTESTINE	PARP1 →	+0.749	+0.611	.007	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,066 associations by consensus.

RRN3 vs TIMELESS — LARGE_INTESTINE

Explore this scatter interactively →