RRM2P4

Across TCGA pan-cancer cohorts, RRM2P4 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RRM2P4 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RRM2P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RRM2P4 expression acts as an unfavorable survival marker.

BRCA, KICH, and PAAD are the cancer types where RRM2P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Tertile	All	0.776	0.965	<.001	120	view →
KICH	DFS	Tertile	All	0.035	0.904	<.001	90	view →
PAAD	OS	Tertile	All	0.037	0.641	<.001	72	view →
STAD	OS	Tertile	III,IV	0.424	0.683	.004	33	view →
LIHC	OS	Tertile	II,III,IV	0.128	0.617	.037	18	view →
LGG	OS	Tertile	All	0.550	0.813	.014	18	view →
GBM	OS	Tertile	All	0.170	0.414	.038	9	view →
LAML	DFS	Tertile	All	0.313	0.600	.046	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RRM2P4–BRCA (OS)

Open the BRCA breakdown →