RRAS2P1

Across TCGA pan-cancer cohorts, RRAS2P1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RRAS2P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RRAS2P1 RNA is repressed in tumor relative to normal tissue. In most cancer types RRAS2P1 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KICH, BRCA, and HNSC are the cancer types where RRAS2P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RRAS2P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	IV	−1.820	<.001	10	view →
BRCA	All	II,III,IV	−0.408	.001	6	view →
HNSC	All	All	+0.627	.005	5	view →
CHOL	Female	All	+0.960	.018	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RRAS2P1–KICH

Open the KICH breakdown →