RRAGB

Across TCGA pan-cancer cohorts, RRAGB Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated RRAGB data layer compared with 23 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher RRAGB Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RRAGB expression acts as an unfavorable survival marker.

UCS, BLCA, and LUSC are the cancer types where RRAGB Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Median	All	0.102	0.688	<.001	36	view →
BLCA	OS	Median	All	0.141	0.687	.003	18	view →
LUSC	OS	Median	All	0.173	0.724	.012	15	view →
LGG	DFS	Median	All	0.190	0.753	.002	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
ESCA	DFS	Median	All	0.045	0.504	<.001	6	view →
SKCM	DFS	Median	III,IV	0.125	0.615	.004	6	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RRAGB–UCS (OS)

Open the UCS breakdown →