RRAD

Across TCGA patient cohorts, RRAD protein abundance is significantly associated with the RNA expression of many other genes, with 10,116 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RRAD-associated genes across cancer lineages are MAMDC2, SMC6, and ECT2. Each is linked with RRAD in more than 4 cancer types. Because this analysis shows association rather than direction, both RRAD-to-partner and partner-to-RRAD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RRAD versus MAMDC2 in UCEC, with a Pearson correlation of 0.22.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRAD→partner) and Y-score (partner→RRAD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MAMDC2 →	+0.902	+0.412	.005	.003	3	5
LSCC	SMC6 →	-0.571	-0.525	.003	.001	3	4
HNSC	ECT2 →	-0.772	-0.743	.007	.002	3	4
LSCC	PTCD3 →	-0.470	-0.437	<.001	.001	3	4
LSCC	SUV39H2 →	-0.474	-0.294	<.001	.004	3	4
LUAD	CFAP221 →	+1.075	+0.567	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,116 associations by consensus.

RRAD vs MAMDC2 — UCEC

Explore this scatter interactively →