RRAD

Across TCGA cell cohorts, RRAD mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RRAD-associated genes across cancer lineages are SMIM23 and RBMY1A1. Each is linked with RRAD in more than 1 cancer types. Because this analysis shows association rather than direction, both RRAD-to-partner and partner-to-RRAD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMIM23 grouped by RRAD-low versus RRAD-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRAD→partner) and Y-score (partner→RRAD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SMIM23 →	+0.022	+5.569	<.001	.001	3	1
BLOOD_Lymphoma	RBMY1A1 →	+0.029	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SMIM23 by RRAD expression — BLOOD_Leukemia

Explore this box plot interactively →