RPUSD2

Across TCGA cell cohorts, RPUSD2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RPUSD2-associated genes across cancer lineages are LBHD2 and SLC9A4. Each is linked with RPUSD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPUSD2-to-partner and partner-to-RPUSD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LBHD2 grouped by RPUSD2-low versus RPUSD2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPUSD2→partner) and Y-score (partner→RPUSD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LBHD2 →	+0.045	+5.569	<.001	.001	3	1
BLOOD_Leukemia	SLC9A4 →	+0.021	+4.147	<.001	.008	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

LBHD2 by RPUSD2 expression — BLOOD_Leukemia

Explore this box plot interactively →