RPUSD1

Across TCGA pan-cancer cohorts, RPUSD1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated RPUSD1 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher RPUSD1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPUSD1 expression acts as an unfavorable survival marker.

GBM, UCEC, and HNSC are the cancer types where RPUSD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Median	All	0.226	0.442	.004	16	view →
UCEC	DFS	Median	II,III,IV	0.449	1.000	.040	4	view →
HNSC	OS	Median	III,IV	0.813	0.943	.036	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

RPUSD1–GBM (DFS)

Open the GBM breakdown →