RPUSD1

Across TCGA patient cohorts, RPUSD1 mutation is significantly associated with the RNA expression of many other genes, with 254 significant associations in total. COAD shows the largest number of these associations.

The most reproducible RPUSD1-associated genes across cancer lineages are CST12P, GAPDHP56, and CDY4P. Each is linked with RPUSD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPUSD1-to-partner and partner-to-RPUSD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CST12P grouped by RPUSD1-low versus RPUSD1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPUSD1→partner) and Y-score (partner→RPUSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CST12P →	+0.099	+4.970	<.001	.005	3	2
SKCM	GAPDHP56 →	+0.039	+4.594	<.001	.008	3	2
COAD	CDY4P →	+0.283	+3.736	<.001	.005	3	2
COAD	RN7SL516P →	+0.422	+5.142	<.001	.002	3	2
COAD	RN7SL700P →	+0.308	+5.251	<.001	<.001	3	2
COAD	RN7SL122P →	+0.562	+4.602	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 254 associations by consensus.

CST12P by RPUSD1 expression — SKCM

Explore this box plot interactively →