RPUSD1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RPUSD1 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. COAD shows the largest number of these associations.

The most reproducible RPUSD1-associated genes across cancer lineages are GMP and Macrophages. Each is linked with RPUSD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RPUSD1-to-partner and partner-to-RPUSD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by RPUSD1-low versus RPUSD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPUSD1→partner) and Y-score (partner→RPUSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECGMP →+0.079+2.348.045.04133
COADMacrophages →+0.025+2.703.005.02931
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GMP by RPUSD1 expression — UCEC

Box plot of GMP in RPUSD1-low vs RPUSD1-high samples in UCEC.

Explore this box plot interactively →

Exploration