Across TCGA patient cohorts, RPTN RNA expression is significantly associated with the protein abundance of many other proteins, with 7,299 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RPTN-associated proteins across cancer lineages are TRIM29, KRT16_S448, and TBC1D2. Each is linked with RPTN in more than 4 cancer types. Because this analysis shows association rather than direction, both RPTN-to-partner and partner-to-RPTN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPTN→partner) and Y-score (partner→RPTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRIM29 →	+1.124	+1.654	<.001	<.001	3	5
LSCC	KRT16_S448 →	+2.704	+1.947	<.001	<.001	3	4
HNSC	TBC1D2 →	+0.420	+2.280	.001	<.001	3	4
PDAC	TRIM29_S21 →	+1.487	+1.305	<.001	<.001	3	4
LSCC	SPRR1A →	+1.644	+1.733	<.001	<.001	3	4
PDAC	SPRR1B →	+1.590	+0.744	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,299 associations by consensus.

Exploration

RPTN survival (RNA) · tumor vs normal (RNA) · all RPTN data types