RPSAP73

Across TCGA pan-cancer cohorts, RPSAP73 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RPSAP73’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPSAP73 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPSAP73 is over-expressed in tumor.

KIRC, HNSC, and COAD are the cancer types where RPSAP73 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPSAP73 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.044	.001	7	view →
HNSC	Male	All	+0.076	.011	3	view →
COAD	All	All	+0.101	.035	2	view →
LIHC	Male	II,III,IV	+0.066	.032	2	view →
BRCA	All	III,IV	+0.034	.039	2	view →
STAD	All	IV	+0.203	<.001	1	view →
LUAD	All	All	+0.054	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RPSAP73–KIRC

Open the KIRC breakdown →