Across TCGA pan-cancer cohorts, RPSAP72 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPSAP72’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RPSAP72 RNA is repressed in tumor relative to normal tissue. In most cancer types RPSAP72 is over-expressed in tumor, although a few such as HNSC and BRCA show the opposite, repressed pattern.

HNSC, BRCA, and THCA are the cancer types where RPSAP72 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPSAP72 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	II,III,IV	−0.144	<.001	6	view →
BRCA	All	III,IV	−0.344	.006	4	view →
THCA	All	All	−0.209	<.001	4	view →
COAD	Male	IV	−0.338	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RPSAP72 RNA expression & survival · all RPSAP72 data types