RPSAP6

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RPSAP6 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RPSAP6 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RPSAP6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPSAP6 expression acts as an unfavorable survival marker, although some lineages such as COAD and READ show a favorable association.

KIRP, COAD, and READ are the cancer types where RPSAP6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRPOSQuartileII,III,IV0.7130.932.01037view →
COADDFSQuartileAll0.8490.708.00233view →
READDFSQuartileAll0.8390.566.00428view →
UCECOSMedianAll0.6000.745.00822view →
BRCADFSTertileII,III,IV0.8620.925.00920view →
UCSDFSMedianIV0.9090.416.00818view →
UVMDFSMedianIII,IV0.9000.291.00512view →
SKCMOSQuartileIII,IV0.8860.774.01512view →
ACCOSQuartileII,III,IV0.2560.660.00810view →
KICHDFSTertileAll0.7281.000.0208view →
LIHCOSQuartileIII,IV0.4210.688.0048view →
CESCOSTertileIV0.0970.576.0476view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

Exploration