Across TCGA pan-cancer cohorts, RPSAP57 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of RPSAP57’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RPSAP57 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPSAP57 is over-expressed in tumor.
HNSC are the cancer types where RPSAP57 tumor–normal differential expression is most reproducible.