Across TCGA pan-cancer cohorts, RPSAP49 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RPSAP49’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where RPSAP49 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPSAP49 is over-expressed in tumor, although a few such as HNSC show the opposite, repressed pattern.
LIHC, COAD, and CHOL are the cancer types where RPSAP49 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPSAP49 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.