RPSAP48

Across TCGA pan-cancer cohorts, RPSAP48 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPSAP48’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPSAP48 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPSAP48 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

KIRC, KIRP, and LUAD are the cancer types where RPSAP48 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPSAP48 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	+0.069	<.001	8	view →
KIRP	Male	II,III,IV	+0.071	.019	5	view →
LUAD	Male	All	+0.040	.029	2	view →
THCA	All	IV	−0.075	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RPSAP48–KIRC

Open the KIRC breakdown →