RPSAP40

Across TCGA pan-cancer cohorts, RPSAP40 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RPSAP40’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RPSAP40 RNA is repressed in tumor relative to normal tissue. In most cancer types RPSAP40 is over-expressed in tumor, although a few such as BRCA and STAD show the opposite, repressed pattern.

BRCA, KIRC, and STAD are the cancer types where RPSAP40 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPSAP40 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	−0.030	<.001	6	view →
KIRC	All	All	+0.025	.005	4	view →
STAD	All	All	−0.023	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RPSAP40–BRCA

Open the BRCA breakdown →