RPSAP31

Across TCGA pan-cancer cohorts, RPSAP31 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RPSAP31’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPSAP31 RNA is repressed in tumor relative to normal tissue. In most cancer types RPSAP31 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and LIHC are the cancer types where RPSAP31 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPSAP31 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	−0.108	<.001	6	view →
KICH	All	All	−0.145	<.001	4	view →
LIHC	All	All	+0.089	<.001	4	view →
THCA	All	All	−0.071	<.001	4	view →
COAD	All	II,III,IV	+0.149	.014	2	view →
LUAD	Female	III,IV	−0.111	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RPSAP31–KIRC

Open the KIRC breakdown →