RPSAP25

Across TCGA pan-cancer cohorts, RPSAP25 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPSAP25’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RPSAP25 RNA is repressed in tumor relative to normal tissue. In most cancer types RPSAP25 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, BRCA, and KICH are the cancer types where RPSAP25 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPSAP25 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.020	.007	3	view →
BRCA	All	III,IV	+0.025	.025	2	view →
KICH	All	All	−0.020	.021	2	view →
KIRC	Female	All	+0.016	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RPSAP25–THCA

Open the THCA breakdown →