RPSAP23

Across TCGA pan-cancer cohorts, RPSAP23 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RPSAP23 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RPSAP23 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RPSAP23 expression acts as an unfavorable survival marker, although some lineages such as LUSC and LUAD show a favorable association.

LUSC, PAAD, and MESO are the cancer types where RPSAP23 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Tertile	All	0.564	0.364	.007	72	view →
PAAD	OS	Tertile	All	0.368	0.626	.004	63	view →
MESO	OS	Tertile	III,IV	0.036	0.563	<.001	54	view →
ACC	DFS	Tertile	II,III,IV	0.158	0.580	<.001	30	view →
ESCA	OS	Tertile	II,III,IV	0.330	1.000	.002	29	view →
SARC	DFS	Tertile	All	0.157	0.515	<.001	27	view →
LUAD	DFS	Tertile	II,III,IV	0.794	0.474	.014	27	view →
BLCA	OS	Tertile	IV	0.195	0.478	.017	18	view →
PCPG	OS	Tertile	All	0.505	0.946	<.001	18	view →
TGCT	DFS	Tertile	All	0.781	0.617	.039	12	view →
STAD	DFS	Tertile	II,III,IV	0.561	0.681	.029	9	view →
THYM	DFS	Tertile	III,IV	0.205	0.774	.007	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

RPSAP23–LUSC (DFS)

Open the LUSC breakdown →