RPSAP22

Across TCGA patient cohorts, RPSAP22 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,904 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RPSAP22-associated GO terms across cancer lineages are Myeloid leukocyte activation, Regulation of antigen processing and presentation, and Response to type II interferon. Each is linked with RPSAP22 in more than 17 cancer types. Because this analysis shows association rather than direction, both RPSAP22-to-partner and partner-to-RPSAP22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myeloid leukocyte activation grouped by RPSAP22-low versus RPSAP22-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPSAP22→partner) and Y-score (partner→RPSAP22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Myeloid leukocyte activation →	+0.042	+0.114	<.001	<.001	3	17
DLBC	Regulation of antigen processing and presentation →	+0.058	+0.150	.006	.002	2	18
STAD	Response to type II interferon →	+0.082	+0.152	<.001	.004	3	17
STAD	Macrophage activation →	+0.058	+0.127	<.001	.001	3	17
UVM	Zymogen inhibition →	+0.062	+0.034	<.001	<.001	3	17
STAD	Negative regulation of innate immune response →	+0.057	+0.107	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,904 associations by consensus.

Myeloid leukocyte activation by RPSAP22 expression — STAD

Explore this box plot interactively →