Across TCGA pan-cancer cohorts, RPSAP19 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPSAP19’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where RPSAP19 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPSAP19 is over-expressed in tumor.
LIHC and KIRP are the cancer types where RPSAP19 tumor–normal differential expression is most reproducible.