RPSAP14

Across TCGA patient cohorts, RPSAP14 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible RPSAP14-associated genes across cancer lineages are RNU6-862P, RNU6-1336P, and HMGN1P19. Each is linked with RPSAP14 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPSAP14-to-partner and partner-to-RPSAP14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-862P grouped by RPSAP14-low versus RPSAP14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPSAP14→partner) and Y-score (partner→RPSAP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-862P →	+0.562	+5.484	.009	.005	3	1
UCEC	RNU6-1336P →	+0.704	+4.982	<.001	.009	3	1
UCEC	HMGN1P19 →	+0.220	+5.484	.003	.005	3	1
LUSC	MIR520G →	+0.308	+7.924	.002	.008	3	1
SKCM	PRAMEF34P →	+0.019	+7.816	<.001	.008	3	1
SKCM	SMIM34B →	+0.029	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

RNU6-862P by RPSAP14 expression — UCEC

Explore this box plot interactively →