RPSAP11

Across TCGA pan-cancer cohorts, RPSAP11 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPSAP11’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where RPSAP11 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPSAP11 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

LIHC, THCA, and COAD are the cancer types where RPSAP11 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPSAP11 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	II,III,IV	+0.116	<.001	6	view →
THCA	All	All	−0.157	<.001	4	view →
COAD	All	All	+0.308	.026	3	view →
CHOL	Male	All	+0.221	.006	2	view →
KICH	Female	All	−0.116	.035	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RPSAP11–LIHC

Open the LIHC breakdown →