Across TCGA pan-cancer cohorts, RPSAP10 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPSAP10’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPSAP10 RNA is repressed in tumor relative to normal tissue. In most cancer types RPSAP10 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.
KIRC and PRAD are the cancer types where RPSAP10 tumor–normal differential expression is most reproducible.